Carboxyl Methylation of Protein Phosphatase 2A from Xenopus Eggs Is Stimulated by cAMP and Inhibited by Okadaic Acid
✍ Scribed by M. Floer; J. Stock
- Book ID
- 115574087
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 358 KB
- Volume
- 198
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A carboxyl‐terminal peptide sequence (“osteostatin”) from parathyroid hormone related protein has been shown to have an inhibitory effect on osteoclastic bone resorption—an action opposite to its amino‐terminal sequence. In this study, we proposed that inhibition of osteoclastic bone re
The involvement of serine/threonine protein phosphatases in signaling pathways that control the expression of the cyclooxygenase-2 (COX-2) gene in human chondrocytes was examined. Okadaic acid (OKA), an inhibitor of protein phosphatases 1 (PP-1) and 2A (PP-2A), induced a delayed, time-dependent incr