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Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases

✍ Scribed by Lushan Yu; Sijie Lu; Yongjun Lin; Su Zeng

Book ID
113488225
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
580 KB
Volume
73
Category
Article
ISSN
0006-2952

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Glucuronidation of curcuminoids by human
Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases
✍ Simone I. Hoehle; Erika Pfeiffer; Manfred Metzler πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 907 KB

## Abstract Glucuronidation is an important pathway in the metabolism of curcumin, but the isoforms of uridine‐5′‐diphosphoglucuronosyltransferase (UGT) involved are not known. Here, we report on the glucuronidation of the three natural curcuminoids and their major phase I metabolites with microsom