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Carbopeptoid Folding: Effects of Stereochemistry, Chain Length, and Solvent

โœ Scribed by Riccardo Baron; Dirk Bakowies; Wilfred F. van Gunsteren

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
233 KB
Volume
116
Category
Article
ISSN
0044-8249

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The kinetics of folding of the two forms of unfolded ribonuclease A have been measured as a function of solvent viscosity by adding either glycerol or sucrose. The aim is to find out if either reaction is rate limited by segmental motion whose rate depends on external friction. The fast folding rea