Carbonylation of terminal alkynes catalysed by Pd complexes in combination with tri(2-furyl)phosphine and methanesulfonic acid

✍ Scribed by Alberto Scrivanti; Valentina Beghetto; Monica Zanato; Ugo Matteoli

• Book ID: 104421102
• Publisher: Elsevier Science
• Year: 2000
• Tongue: English
• Weight: 111 KB
• Volume: 160
• Category: Article
• ISSN: 1381-1169
• DOI: 10.1016/s1381-1169(00)00309-5

✦ Synopsis

Ž

. Ž . Pd OAc in combination with tri 2-furyl phosphine and methanesulfonic acid is an efficient catalyst for the alkoxycar-2 Ž Ž . . bonylation of 1-alkynes. Fairly good reaction rates are obtained under mild conditions 50-808C and P CO s 20 bar with Ž . high regioselectivity ca. 95% towards the formation of 2-substituted acrylic ester.