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Carbonic anhydrase-related protein VIII increases invasiveness of non-small cell lung adenocarcinoma

✍ Scribed by Tsuyoshi Ishihara; Tamotsu Takeuchi; Isao Nishimori; Yoshihiro Adachi; Tomoko Minakuchi; Jiro Fujita; Hiroshi Sonobe; Yuji Ohtsuki; Saburo Onishi

Book ID: 106117563
Publisher: Springer
Year: 2006
Tongue: English
Weight: 505 KB
Volume: 448
Category: Article
ISSN: 1432-2307
DOI: 10.1007/s00428-006-0199-0

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## Abstract The pattern of protein expression in tumors is under the influence of nutrient stress, hypoxia and low pH, which determines the survival of neoplastic cells and the development of tumors. Carbonic anhydrase XII (CAXII) is a transmembrane enzyme that catalyzes the reversible hydration of