Carbon Dioxide Laser Treatment of Vaginal Adenosis in DES-Exposed Offspring: A Prospective Study

✍ Scribed by Joseph H. Bellina; Lynne Fischer Ross; Robert Hemmings; Janos I. Voros; Myron Moorehead

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: English
• Weight: 351 KB
• Volume: 3
• Category: Article
• ISSN: 0196-8092
• DOI: 10.1002/lsm.1900030104

✦ Synopsis

Seventy-nine patients with history and physical findings characteristic of antenatal DES exposure were randomly divided into two groups. Fourty-four DES-exposed offspring had their vaginal adenosis treated with the carbon dioxide laser (group I), and the remaining 35 DES-exposed offspring (group II) did not receive any specific treatment for this condition. Additionally, the 79 DESexposed offspring were compared to an age-matched control population (group III). Treatment of vaginal adenosis with the carbon dioxide laser did not significantly reduce the incidence of development of new dysplasia in the DES-exposed offspring. This study also showed no statistical difference (p Q 0.05) in the incidence of dysplasia in DES-exposed offspring as compared to a control population.