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Carbon-11, nitrogen-13 and oxygen-15 — labelled molecules

✍ Scribed by Crouzel, Christian; Comar, Dominique

Book ID
122344202
Publisher
Elsevier Science
Year
1986
Weight
361 KB
Volume
13
Category
Article
ISSN
0883-2897

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Syntheses of colchicine and isocolchicin
Syntheses of colchicine and isocolchicine labelled with carbon-11 or carbon-13
✍ Paresh J. Kothari; Ronald D. Finn; Steven M. Larson 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The syntheses of isotopically labelled (−)‐10‐[^11^C/^13^C]‐colchicine and (−)‐9‐[^11^C/^13^C]‐ isocolchicine have been achieved from the reaction of (−)desmethylcolchicine with [^11^C/^13^C]‐iodomethane. The radiolabelled compounds, (−)‐10‐[^11^C]‐colchicine (^11^C‐n‐colchicine) and (−