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Carbon-11 labeled radioligands for imaging brain cannabinoid receptors

โœ Scribed by William B Mathews; Ursula Scheffel; Paige A Rauseo; Hayden T Ravert; Richard A Frank; George J Ellames; John M Herbert; Francis Barth; Murielle Rinaldi-Carmona; Robert F Dannals


Book ID
117687844
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
189 KB
Volume
29
Category
Article
ISSN
0969-8051

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Preparation of iodine-123 labeled AM251:
โœ Ruoxi Lan; S. John Gatley; Alexandros Makriyannis ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 361 KB ๐Ÿ‘ 1 views

We report the synthesis and labeling with iodine-123 of N-(piperidin-1-yl)-5-(4-iodophenyl)-l-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (AM251). This compound is an analog of the recently described cannabinoid receptor antagonist, SR1417164 in which a 4-chlorophenyl group is replaced b