✦ LIBER ✦

Carbometallation of 5-ethynyl-pyrimidine-2′-deoxy nucleosides: Preparation of 5-(1-[E]-butenyl)- and 5-(3-[E]-hex-3-enyl)-2′-deoxyuridine

✍ Scribed by Stanislas Czernecki; Antoine Hoang; Jean-Marc Valéry

Book ID: 104214453
Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 274 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)73231-x

No coin nor oath required. For personal study only.

✦ Synopsis

The regioselecrivity of rhe carbomelaltation of S-erhynyl-2*-deoxy-t&dine with orgonocopper reagents is completely conwolkd in on onli

-Markovnikov way by the oxygen atom at C-4. Hydrolysis or akylolion Op tht resulting vinylwpper &riw've @ord resprcn'vely S-(i-1~1~b~enyl)_ and 543-~E]-hts3~ny&2'&qwridk.

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