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Carbohydrates in organic synthesis. Synthesis of 16-membered-ring macrolide antibiotics. 5. Total synthesis of O-mycinosyltylonolide: synthesis of key intermediates

✍ Scribed by Nicolaou, K. C.; Pavia, M. R.; Seitz, S. P.


Book ID
120244414
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
386 KB
Volume
104
Category
Article
ISSN
0002-7863

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Synthesis of 16-membered ring macrolide
✍ K.C. Nicolaou; M.R. Pavia; S.P. Seitz πŸ“‚ Article πŸ“… 1979 πŸ› Elsevier Science 🌐 French βš– 227 KB

D-Glucose was converted to a backbone chain containing the appropriate functionalities an correc7 stereochemistry for the construction of the Cl-C9 fragment of the 16-membered ring macrolide antibiotics carknycin A and B and leuccqzin A3. Ieucctnycin AS and carkmycins A and B (magnamycins A and B) s