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Carbohydrates as chiral templates: Diastereoselective Ugi synthesis of (S)-amino acids using O-acylated D-arabinopyranosylamine as the auxiliary

✍ Scribed by Horst Kunz; Waldemar Pfrengle; Wilfried Sager


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
151 KB
Volume
30
Category
Article
ISSN
0040-4039

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Carbohydrates as chiral templates: Stere
✍ Kunz, Horst ;Sager, Wilfried ;Schanzenbach, Dirk ;Decker, Mathias 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 698 KB

## Abstract The asymmetric synthesis of __N__‐galactosyl D‐α‐amino nitriles is accomplished by application of 2,3,4,6‐tetra‐__O__‐pivaloyl‐β‐D‐galactopyranosylamine (4) as the stereodifferentiating template in Strecker reactions. Aldimines 6 derived from 4 and aromatic or aliphatic aldehydes react