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Carbohydrate structures in the β-subunit of human chorionic gonadotropin play a dominant role in hormonal activity

✍ Scribed by Yasuyuki Shimohigashi; Hao-Chia Chen


Book ID
115914108
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
402 KB
Volume
150
Category
Article
ISSN
0014-5793

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The beta-subunit of the human chorionic gonadotropin (hCG) hormone, which is believed to be related to certain types of cancer, contains three hairpin-like fragments. To investigate the role of beta-hairpin formation in the early stages of the hCGbeta folding, a 28-residue peptide with the sequence