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Carbohydrate-specific monoclonal antibodies bind to human granulocytes and stimulate antibody-dependent cellular cytotoxicity

โœ Scribed by P.F. Spitalnik; S.L. Spitalnik; J.M. Danley; A.F. Lopez; M.A. Vadas; C.I. Civin; V. Ginsburg


Book ID
115708131
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
928 KB
Volume
271
Category
Article
ISSN
0003-9861

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Human peripheral blood mononuclear cells (lymphocytes and monocytes) were preincubated for 0-24 h with human recombinant granulocyte-monocyte-colony-stimulating factor (GM-CSF) and used as effector cells in an 18 h antibody-dependent cellular cytotoxicity (ADCC) assay with SW948 (a human colorectal