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Carbohydrate recognition and complement activation by rat ficolin-B

✍ Scribed by Umakhanth Venkatraman Girija; Daniel A. Mitchell; Silke Roscher; Russell Wallis


Book ID
102163600
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
333 KB
Volume
41
Category
Article
ISSN
0014-2980

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Complement is an essential innate immune mechanism that recognizes and eradicates microbes and associated toxins. In addition, complement receptors (CD21 and CD35) on B cells cooperate with the B-cell antigen receptor (BCR) to efficiently recognize and respond to antigens bearing complement C3d(g).