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Carbohydrate-Functionalized Dendrimers To Investigate the Predictable Tunability of Multivalent Interactions

โœ Scribed by Wolfenden, Mark L.; Cloninger, Mary J.


Book ID
118148318
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
303 KB
Volume
17
Category
Article
ISSN
1043-1802

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## Abstract We have developed an iterative knowledgeโ€based scoring function (ITScore) to describe proteinโ€“ligand interactions. Here, we assess ITScore through extensive tests on native structure identification, binding affinity prediction, and virtual database screening. Specifically, ITScore was f