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Carbohydrate Composition of Peripheral, Cultured and Leukaemic Human Lymphocyte Plasma Membranes

✍ Scribed by Newman, R.A. ;Glöckner, W.M. ;Uhlenbruck, G.

Book ID
122396885
Publisher
Elsevier
Year
1978
Weight
896 KB
Volume
154
Category
Article
ISSN
0340-904X

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Plasma membranes purified 32to 45-fold were isolated from leukaemic T-lymphoblasts, both sensitive and resistant to the Vinca alkaloid vinblastine. On development of drug resistance there was a very significant elevation of ether lipid content. I-0-alkyl phospholipid increased by 200% with a smaller