Carbimazole embryopathy-bilateral choanal atresia and patent vitello-intestinal duct: A case report and review of literature
✍ Scribed by Lakshminarayanan Kannan; Satish Mishra; Ramesh Agarwal; Venkat Kartikeyan; Neerja Gupta; Madhulika Kabra
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 98 KB
- Volume
- 82
- Category
- Article
- ISSN
- 1542-0752
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✦ Synopsis
Abstract
BACKGROUND: In utero exposure to carbimazole for maternal hyperthyroidism has been reported to cause choanal atresia. There are case reports of patent vitello‐intestinal duct and Meckel's diverticulum in similar association. CASE: We report another such instance of an infant who was exposed to carbimazole in utero, presenting with bilateral choanal atresia and patent vitello‐intestinal duct. CONCLUSIONS: As there seems to be no reports of a possible association between propylthiouracil and congenital malformations, it may be safer to use propylthiouracil instead of carbimazole. Birth Defects Research (Part A), 2008. © 2008 Wiley‐Liss, Inc.