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Carbenoxolone inhibits DNA synthesis and collagen gene expression in rat hepatic stellate cells in culture

✍ Scribed by Naoki Uyama; Yasuyuki Shimahara; Hiroaki Okuyama; Norifumi Kawada; Shoko Kamo; Kazuo Ikeda; Yoshio Yamaoka

Book ID
117371998
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
311 KB
Volume
39
Category
Article
ISSN
0168-8278

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## Abstract Leptin is a 16‐kDa hormone with an array of biologic actions. We, and others, have demonstrated that leptin is critical to the development of liver fibrogenesis both in vitro and in the lean littermates of __ob__/__ob__ mice exposed to carbon tetrachloride (CCl~4~). Controversy exists a