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Carbanions as Intermediates in the Synthesis of Grignard Reagents

โœ Scribed by Drs. Henricus J. R. de Boer; Dr. Otto S. Akkerman; Prof. Dr. Friedrich Bickelhaupt


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
365 KB
Volume
27
Category
Article
ISSN
0044-8249

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ChemInform Abstract: Diastereoselective
โœ R. H. MUELLER; S. WANG; P. D. PANSEGRAU; J. Q. JANNOTTI; M. A. POSS; J. K. THOTT ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB ๐Ÿ‘ 1 views

Diastereoselective Reaction of a Grignard Reagent with Chiral Imides: A Practical Preparation of a Key Intermediate in the Synthesis of Ifetroban Sodium. -The synthesis of the key intermediate (VIII) of ifetroban sodium is achieved via efficient formation of the chiral imine (IV) and its diastereose