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Carbachol inhibition of Ca2+ currents in ventricular cells obtained from neonatal and adult rats

โœ Scribed by Yasuhiro Katsube; Hisashi Yokoshiki; Masanori Sunagawa; Takashi Seki; Masao Yamamoto; Nicholas Sperelakis

Book ID
114016606
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
166 KB
Volume
358
Category
Article
ISSN
0014-2999

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In freshly dispersed rat parotid acinar cells, 10 microM carbachol increased outward currents at 0 mV and also inward currents at -70 mV recorded with the wholecell clamp method using patch pipettes containing 1 mM EGTA. When EGTA in the pipette was increased to 2.4 mM, carbachol increased only outw