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Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells

✍ Scribed by Xiaohua Jiang; James Sinnett-Smith; Enrique Rozengurt

Book ID: 117981635
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 314 KB
Volume: 387
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2009.07.060

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## Abstract Ascochlorin, a non‐toxic prenylphenol compound derived from the fungus __Ascochyta viciae__, has been shown recently to have anti‐cancer effects on various human cancer cells. However, the precise molecular mechanism of this anti‐cancer activity remains to be elucidated. Here, we invest