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✦   LIBER   ✦

Capsid modification of adeno-associated virus and tumor targeting gene therapy

✍ Scribed by Xu, ZengHui ;Zhou, XiuMei ;Shi, WenFang ;Qian, QiJun

Book ID
107368618
Publisher
Elsevier
Year
2008
Tongue
English
Weight
729 KB
Volume
53
Category
Article
ISSN
2095-9273

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## Abstract To evaluate the tumoricidal activity of tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) on disseminated liver metastatic tumors, we constructed a recombinant adeno‐associated virus (rAAV) expressing the extracellular domain (95–281aa) of human TRAIL (TRAIL~95–281~,