✦ LIBER ✦

Capped Oligodeoxynucleotide Phosphorothioates. : Pharmacokinetics and Stability in Mice

✍ Scribed by J. TEMSAMANI; J.-Y. TANG; SUDHIR AGRAWAL

Book ID: 119866975
Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 276 KB
Volume: 660
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1992.tb21099.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Biodistribution and pharmacokinetics of

Biodistribution and pharmacokinetics of antisense phosphorothioate oligodeoxynucleotide in mice

✍ Z.Q. Yao; A.Q. Huang; S.H. Yap 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 163 KB

End-capped antisense oligodeoxynucleotid

End-capped antisense oligodeoxynucleotides effectively inhibit gene expression in vivo and offer a low-toxicity alternative to fully modified phosphorothioate oligodeoxynucleotides

✍ M.O Hebb; H.A Robertson 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 628 KB

Organ distribution and stability of phos

Organ distribution and stability of phosphorothioated oligodeoxyribonucleotides in mice

✍ Goodarz Goodarzi; Misako Watabe; Kounosuke Watabe 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 332 KB

## Abstract Results of recent studies in our laboratory have suggested a potential role for antisense oligodeoxyribonucleotides (oligo(dN)s) as therapeutic agents in the treatment of human hepatitis B virus infection. As a first step towards assessing the potential utility of oligo(dN) in therapy,

CORRIGENDUM: Pharmacokinetics of an anti

CORRIGENDUM: Pharmacokinetics of an anti–human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects

📂 Article 📅 2011 🏛 Nature Publishing Group 🌐 English ⚖ 39 KB

A Rapid Method for Quantitation of Oligo

A Rapid Method for Quantitation of Oligodeoxynucleotide Phosphorothioates in Biological Fluids and Tissues

✍ J. Temsamani; M. Kubert; S. Agrawal 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 339 KB

A sensitive and simple method for the quantitation of oligonucleotide phosphorothioates in biological fluids and tissues is described. This method is based on the extraction of the oligonucleotide from the biological fuids and tissues and immobilization on a nylon membrane. The membrane-bound oligod

In vivo inhibition of hepatitis B viral

In vivo inhibition of hepatitis B viral gene expression by antisense phosphorothioate oligodeoxynucleotides in athymic nude mice

✍ Yao Zhiqiang; Zhou Yongxing; Feng Xiemei; Chen Chongxin; Guo Jun 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 754 KB