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Capillary tube leukocyte adherence inhibition: An assay for cell-mediated immunity in cancer patients

✍ Scribed by Marshall M. Urist; Arthur W. Boddie Jr.; E. Carmack Holmes; Donald L. Morton


Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
328 KB
Volume
17
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

The leukocyte adherence inhibition (LAI) assay has been modified and automated in order to facilitate its clinical application. This new assay‐the capillary tube LAI test‐correlated with delayed cutaneous hypersensitivity using streptokinase‐streptodornase antigen in 83% of the cases. When tested with a 3 m KCI lung carcinoma antigen, lung carcinoma patients' leukocytes were more frequently inhibited (55%) than those of controls (normals 6%, other tumors 20%).


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