✦ LIBER ✦

Capillary affinophoresis as a versatile tool for the study of biomolecular interactions: a mini-review

✍ Scribed by Kiyohito Shimura; Ken-ichi Kasai

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 111 KB
Volume: 11
Category: Article
ISSN: 0952-3499
DOI: 10.1002/(sici)1099-1352(199812)11:1/6<134::aid-jmr409>3.0.co;2-g

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✦ Synopsis

Combination of capillary electrophoresis and bioaffinity interaction gave rise to powerful research tools for analyzing molecular recognition. They take advantages of the electrophoretic behavior of the complex formed between a target biomolecule and a specially designed mobile ligand molecule (affinophore or affinity probe), and enable detection of complex formation, determination of the equilibrium constants and stoichiometry, etc.