Capecitabine chemoradiotherapy in locally advanced head and neck cancer—An alternative to cisplatin?
✍ Scribed by L. Mais; N.J. Slevin; A.J. Sykes; B.K. Yap; R. Swindell
- Book ID
- 119518243
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 166 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0167-8140
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## Abstract ## Background. In locally advanced head and neck cancer, concurrent chemoradiotherapy (CRT) with combined 5‐fluorouracil (5‐FU) and cisplatin has increased acute toxicities as well as survival. Once‐weekly chemotherapeutic administration schedule may reduce severe toxicities. Thus, we
Background. To investigate neck control probability and the value of nodal response at completion of alternating chemoradiotherapy, a group of 43 patients was reviewed. Methods. Patients were treated with 60 Gy alternated with four cycles of cisplatin and fluorouracil. All patients had lymph nodes