Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments

Dual regulation of astrocyte gap junctio

Dual regulation of astrocyte gap junction hemichannels by growth factors and a pro-inflammatory cytokine via the mitogen-activated protein kinase cascade

✍ Mitsuhiro Morita; Chihiro Saruta; Nagisa Kozuka; Yoshiumi Okubo; Makoto Itakura; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB

## Abstract Evidence that glutamate and ATP release from astrocytes can occur via gap junction hemichannels (GJHCs) is accumulating. However, the GJHC is still only one possible release mechanism and has not been detected in some studies, although this may be because the levels were below those det