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✦   LIBER   ✦

Cannabinoids and the Brain || An Historical Introduction to the Endocannabinoid and Endovanilloid Systems

✍ Scribed by Köfalvi, Attila


Book ID
120360650
Publisher
Springer US
Year
2008
Tongue
English
Weight
101 KB
Edition
2008
Category
Article
ISBN
0387743499

No coin nor oath required. For personal study only.

✦ Synopsis


Endocannabinoids control most of the body functions, and in the brain, they modulate neurotransmission, synaptic plasticity, confer neuroprotection, control metabolism, neuro- and neuritogenesis, survival, cognitive and motor functions as well as a plethora of other higher-order brain functions. Their fruitful therapeutic potential is recognized by cannabinoid researchers and pharmaceutical companies, respectively. The aim of this book is to help clinicians, neuroscientists, as well as students, understand the significance of the endocannabinoid system. This book, however, also will be very useful to those who already feel comfortable with the neuroscience of endocannabinoids. The book will introduce the reader to the “up-to-date” neurobiology of endocannabinoids and related systems, and will detail their pathophysiological role and therapeutic potential. Authors involved in clinical investigations present results of recent clinical trials, and the development of new therapeutic strategies and medicines.


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An introduction to the endocannabinoid s
✍ Luciano De Petrocellis; Vincenzo Di Marzo 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 390 KB

A rather complex and pleiotropic endogenous signalling system was discovered in the late 1990s, starting from studies on the mechanism of action of Delta(9)-tetrahydrocannabinol, the major psychoactive principle of the hemp plant Cannabis sativa. This system includes: (1) at least two G-protein-coup