## Abstract We have previously reported that activation of the G protein coupled calcium‐sensing receptor (CaSR) by extracellular Ca^2+^ down‐modulates the expression of thymidylate synthase (TS) and survivin and promotes sensitivity to fluorouracil in human colon carcinoma cells. Here, we report f
✦ LIBER ✦
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil
✍ Scribed by Sofia B. Gustafsson; Theres Lindgren; Maria Jonsson; Stig O. P. Jacobsson
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 823 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0344-5704
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Gamma-Interferon (IFN-y) and the antimetabolites 5fluorouracil(5-FU) and 5-fluoro-2'-deoxyuridine (FUdR) were investigated as individual agents and in combination for their in vitro antiproliferative capacity and for their effect on the expression of HLA class-I antigen, carcinoembryonic antigen (CE