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Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line

✍ Scribed by A. B. El-Remessy; M. Rajesh; P. Mukhopadhyay; B. Horváth; V. Patel; M. M. H. Al-Gayyar; B. A. Pillai; P. Pacher


Publisher
Springer
Year
2011
Tongue
English
Weight
523 KB
Volume
54
Category
Article
ISSN
0012-186X

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN