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Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism

✍ Scribed by Angelo Vaccani; Paola Massi; Arianna Colombo; Tiziana Rubino; Daniela Parolaro


Book ID
110008648
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
137 KB
Volume
144
Category
Article
ISSN
0007-1188

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We investigated the possible involvement of HTLV-1 Tax in the transcriptional activation of p21/Waf1/Cip1 (hereafter p21), a potent inhibitor of cyclin-dependent kinases and cell growth. Tax transfection resulted in enhanced expression of p21 protein in T and fibroblastoid cells. Similarly, Tax-expr