A new gas chromatographic/mass spectrometric method in combination with isotope dilution for the determination of thyroxine in serum is described. Special attention was paid to the methylation step of thyroxine, which was investigated using methanolic HCI, dimethylformamide/dimethylacetal and diazom
✦ LIBER ✦
Candidate Reference Method for Determining Serum Cortisol Based on Isotope Dilution–Gas Chromatography/Mass Spectrometry Using Heptafluorobutyrilation as Derivatization Method
✍ Scribed by Linda M. Thienpont; Veronique I. De Brabandere; Dietmar Stöckl; André P. De Leenheer
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 90 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Development of a new method for the dete
✍
Linda M. Thienpont; Veronique I. De Brabandere; Dietmar Stöckl; André P. De Leen
📂
Article
📅
1994
🏛
John Wiley and Sons
🌐
English
⚖ 668 KB
Isotope dilution-liquid chromatography/e
✍
Veronique I. De Brabandere; Pin Hou; Dietmar Stöckl; Linda M. Thienpont; André P
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 68 KB
👁 2 views
A new candidate reference method is presented for the determination of thyroxine in serum. The method is based on isotope dilution-liquid chromatography/tandem mass spectrometry using electrospray for ionization. The internal standard used was 13 C 6 -thyroxine, sample pretreatment consisted of prot