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Candida antarctica Lipase B: An Ideal Biocatalyst for the Preparation of Nitrogenated Organic Compounds

✍ Scribed by Vicente Gotor-Fernández; Eduardo Busto; Vicente Gotor


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
442 KB
Volume
348
Category
Article
ISSN
1615-4150

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## Abstract Candida antarctica __lipase B (CAL‐B) catalyzes the regioselective acylation of natural thymidine with oxime esters and also the regioselective acylation of an analogue, 3′,5′‐diamino‐3′,5′‐dideoxythymidine with nonactivated esters. In both cases, acylation favors the less hindered 5′‐p