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Cancer: the matrix is now in control

โœ Scribed by Comoglio, Paolo M; Trusolino, Livio


Book ID
109931896
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
521 KB
Volume
11
Category
Article
ISSN
1078-8956

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Remodelling of extracellular matrix (ECM) and basement membranes is a key component of the process of tumour cell invasion and metastasis. Matrix metalloproteinases (MMPs) are one of the major classes of enzymes involved in degrading ECM, having different substrate specificities and being inhibited