Hereditary non-polyposis colorectal cancer (HNPCC), the most common hereditary colon cancer syndrome, is a dominant disorder caused by germline defects in mismatch repair (MMR) genes. Identification of MMR gene mutations can have direct clinical implications in counseling and management of HNPCC fam
β¦ LIBER β¦
Cancer Risks Associated With Germline Mutations in MLH1, MSH2, and MSH6 Genes in Lynch Syndrome
β Scribed by Bonadona, V.; Bonaiti, B.; Olschwang, S.; Grandjouan, S.; Huiart, L.; Longy, M.; Guimbaud, R.; Buecher, B.; Bignon, Y.-J.; Caron, O.
- Book ID
- 115478658
- Publisher
- American Medical Association
- Year
- 2011
- Tongue
- English
- Weight
- 201 KB
- Volume
- 305
- Category
- Article
- ISSN
- 0098-7484
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Germline mutations in MLH1, MSH2 and MSH
β
Young-Kyoung Shin; Seung-Chul Heo; Joo-Ho Shin; Sung-Hye Hong; Ja-Lok Ku; Byong-
π
Article
π
2004
π
John Wiley and Sons
π
English
β 237 KB
π 1 views
Six novel heterozygous MLH1, MSH2, and M
β
Jean-Marc Rey; Mehrdad Noruzinia; Jean-Paul Brouillet; Pierre Sarda; Thierry Mau
π
Article
π
2004
π
Elsevier Science
π
English
β 148 KB
The PREMM1,2,6 Model Predicts Risk of ML
β
Fay Kastrinos; Ewout W. Steyerberg; Rowena Mercado; Judith BalmaΓ±a; Spring Holte
π
Article
π
2011
π
Elsevier Science
π
English
β 720 KB
Erratum: Germline mutations in MLH1, MSH
β
Young-Kyoung Shin; Seung-Chul Heo; Joo-Ho Shin; Sung-Hye Hong; Ja-Lok Ku; Byong-
π
Article
π
2005
π
John Wiley and Sons
π
English
β 16 KB
π 1 views
Ten novel MSH2 and MLH1 germline mutatio
β
Stefan KrΓΌger; Andrea Bier; Jens Plaschke; Ruth HΓΆhl; Daniela E. Aust; Friedmar
π
Article
π
2004
π
John Wiley and Sons
π
English
β 65 KB
π 1 views
Hereditary nonpolyposis colorectal cancer (HNPCC) is one of the most common hereditary cancer-susceptibility syndromes. Germline mutations in mismatch repair genes are associated with the clinical phenotype of HNPCC. We report ten novel germline mutations, three in MSH2 and seven in MLH1. All but on
Seven novel MLH1 and MSH2 germline mutat
β
Stefan KrΓΌger; Jens Plaschke; Steffen Pistorius; Birgit Jeske; Stephan Haas; Hei
π
Article
π
2001
π
John Wiley and Sons
π
English
β 32 KB
π 1 views