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Cancer risks among iron and steel workers in Anshan, China, part I: Proportional mortality ratio analysis

✍ Scribed by Zhaoyi Xu; Guo-Wei Pan; Li-Ming Liu; Linda Morris Brown; De-Xian Guan; Qiao Xiu; Jia-Hua Sheng; B. J. Stone; Mustafa Dosemeci; Joseph F. Fraumeni Jr.; William J. Blot


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
494 KB
Volume
30
Category
Article
ISSN
0271-3586

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✦ Synopsis


A standardized proportional mortality ratio (SPMR) study of 8,887 deaths during [1980][1981][1982][1983][1984][1985][1986][1987][1988][1989] among male workers in a large integrated iron-steel complex in Anshan, China, was conducted to provide clues to occupational risk factors. Accidents and cancer accounted for a higher proportion of deaths among the iron-steel workers than among the general male population (SPMR = 1.21; 95% Cl = 1.12-1.31 and 1.14; 95% Cl = 1. 10-1.18, respectively). Among all workers, SPMRs were significantly elevated for stomach, lung, and colorectal cancers (SPMR = 1. 37, 1.37, 1.38, respectively), but not other cancers. Risks of stomach cancer appeared to be highest among workers employed in jobs with exposure to iron and coal dust, whereas significant increases in colorectal cancer were seen for loading and other dusty jobs and for administrative and sedentary jobs without dust exposure. Risks of lung cancer appeared increased far a variety of jobs throughout the complex, especially those with probable high levels of exposure to polycyclic hydrocarbons and asbestos. Risk of esophageal cancer was significantly elevated for fire-resistant brick makers, and risk of nonmalignant respiratory disease was significantly elevated for those employed as furnace workers, foundry workers, and fire-resistant brick makers.