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CANCER RESEARCH:A Surprising Function for the PTEN Tumor Suppressor

✍ Scribed by Hopkin, K.

Book ID
121160212
Publisher
American Association for the Advancement of Science
Year
1998
Tongue
English
Weight
250 KB
Volume
282
Category
Article
ISSN
0036-8075

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## Abstract Germline mutations in the tumor‐suppressor gene __PTEN__ (__MMAC1, TEP1__) are found in Cowden syndrome, which predisposes to hamartomas, breast cancer, trichilemmomas, and thyroid tumors of follicular epithelium. __PTEN__ has also been found to be somatically deleted, mutated, and/or s