p53 Website and analysis of p53 gene mut
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Thierry Soussi; Karim Dehouche; Christophe BΓ©roud
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Article
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2000
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John Wiley and Sons
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English
β 331 KB
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The p53 tumor suppressor gene has proven to be one of the genes most often mutated in human cancers. It involves mainly point mutations leading to amino acid substitutions in the central region of the protein which impairs normal functions. Analysis of the mutational events that target the p53 gene