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Cancer Research: New Gene Forges Link Between Fragile Site and Many Cancers

✍ Scribed by Pennisi, E.


Book ID
121156111
Publisher
American Association for the Advancement of Science
Year
1996
Tongue
English
Weight
210 KB
Volume
272
Category
Article
ISSN
0036-8075

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The p53 tumor suppressor gene has proven to be one of the genes most often mutated in human cancers. It involves mainly point mutations leading to amino acid substitutions in the central region of the protein which impairs normal functions. Analysis of the mutational events that target the p53 gene