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Cancer of the uterine cervix may be significantly associated with a gene polymorphism coding for increased IL-10 production

✍ Scribed by Grazyna A. Stanczuk; Elopy N. Sibanda; Chris Perrey; Mike Chirara; Vera Pravica; Ian V. Hutchinson; Sam A. Tswana


Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
55 KB
Volume
94
Category
Article
ISSN
0020-7136

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✦ Synopsis


The purpose of our prospective, case-controlled study was to investigate the hypothesis that women who are genetically programmed to produce high or medium levels of IL-10 were more likely to develop cancer of the uterine cervix than individuals genetically predisposed to low IL-10 production. The population was recruited from patients attending gynecological clinics at 2 hospitals in Harare, Zimbabwe. Laboratory tests were performed in the Departments of Immunology, Chemical Pathology and