Background. Squamous cell carcinomas of the base of the tongue often are diagnosed at advanced stages, in a context of undernutrition with a history of smoking and alcoholism. The local treatment of these tumours is based on external irradiation, either alone or combined with brachytherapy, followed
Cancer of the tongue: Local control of the primary
β Scribed by Major Virendra S. Saxena
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 410 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
The purpose of this study was t o evaluate the effectiveness of radiotherapy in local control of primary cancer of the tongue. A determinate group of 440 patients with this cancer treated from 1945-1959 a t one institute were studied. I t was found that radiotherapy controlled the local disease in 55.4, 50.0, 35.5, and 20.4 percent of the patients initially, b u t subsequent a n d further management by surgey and/or radiotherapy brought this local control rate up to 71.8, 82.0, 46.9, and 25.0 percent in TI, T,, T,, a n d T, cancers of the tongue. T h e fate of all the patients whether alive, alive with recurrence, dead, or dead with or without disease a t the end of 1, 3, 5, a n d 10 years is given in detail. No attempt is made to present author's opinions based upon this study. N MARCH 1967, THE AUTHOR AND D R . I W.E.C. Allt published a study based on 456 cases with cancer of the tonque seen at Ontario Cancer Institute in Toronto between 1945 and 1959.1 It dealt with incidence of sex, age, staging, site of involvement, histology, treatment, 5-and 10-year crude survival rates, and contained a brief discussion of etiologic factors in this group of patients with cancer of the tongue.
T h e basis of this paper is to report the results of different radiotherapeutic techniques used in this cancer and to relate the 1-, 3-, 5, and 10-year crude survival, as well as to compute the local recurrence-free state in cancer of the tongue. T h e fate of the patients whose cancer recurred locally after a curative course of radiotherapy is also discussed. A report of the secondary involvement of cervical lymph nodes from cancer of the tongue, in this group of patients, and its
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