Greater Poland is a region of high cancer risk in Poland. Standardized rates for cancer incidence among man and woman are the highest in Poland. Standardized rates for cancer deaths are also very high (4 th place for men and 2 nd for woman). When analysing the absolute numbers of cases and deaths among men in Greater Poland for last eight years, we observe increase of cases number by 16,14% and deaths by 10,85%. Most common cancer incidence sites in Greater Poland for man are: lung, colorectum and prostate. Among woman breast, colorectum and lung. Most common cancer deaths sites in men are: lung, colorectum and stomach. Among woman breast, lung and colorectum. When analysing standardized rates for malignant tumors morbidity and mortality among men and women, we see clearly that increase of number of new cancer cases and deaths is determined fi rst of all by ageing in Greater Poland population. Lung cancer in Greater Poland is situated in fi rst three most common cancer sites by incidence and mortality. Region has a medium lung cancer incidence and mortality compare to other voivodships. In analyzed period (1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006) lung cancer incidence and mortality among men has decreased. Unfortunately the same trend is not observed among women. High breast cancer incidence is very typical for Greater Poland. Analysis of standardized rates shows that Greater Poland is on 3 rd place by breast cancer incidence and on the 4 th place by breast cancer mortality. The most important and at the same time the cheapest method to eliminate tumors is prophylactics and screening.