✦ LIBER ✦

Cancer in connective tissue disease

✍ Scribed by K. A. Black; P. J. Zilko; R. L. Dawkins; B. K. Armstrong; G. L. Mastaglia

Publisher: John Wiley and Sons
Year: 1982
Tongue: English
Weight: 300 KB
Volume: 25
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780250916

No coin nor oath required. For personal study only.

✦ Synopsis

The risk of cancer appears to be increased in polymyositis (PM) although not all agree with this interpretation (1-5). In other related diseases the risk is probably lower (6-9) but there has not been assessment in mixed connective tissue disease (MCTD). Since it is now possible to separate mixed connective tissue disease from polymyositis, systemic lupus erythematosus (SLE), and progressive systemic sclerosis (PSS), at least serologically, it should be possible to determine whether the increased risk applies to mixed connective tissue disease, polymyositis, or neither.

We used strict criteria (10-14) to classify patients followed in a single center. After allowing for age, sex, and years of followup, we compared cancer rates with those found in an Australian population.

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