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Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

✍ Scribed by Gajewski, Thomas F; Woo, Seng-Ryong; Zha, Yuanyuan; Spaapen, Robbert; Zheng, Yan; Corrales, Leticia; Spranger, Stefani


Book ID
120176552
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
760 KB
Volume
25
Category
Article
ISSN
0952-7915

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## Abstract The pliability of cancer cells to mutate into several different phenotypes in an attempt to find one that will survive and colonize at the metastatic site is a tremendous β€œhurdle” to overcome in designing novel cancer therapeutics. New targets of therapy are essential if we are to effec