Cancer immunoediting from immune surveillance to immune escape
β Scribed by Ryungsa Kim; Manabu Emi; Kazuaki Tanabe
- Book ID
- 108782084
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 575 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0019-2805
No coin nor oath required. For personal study only.
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The concept that the immune system can recognize and destroy nascent transformed cells was originally embodied in the cancer immunosurveillance hypothesis of Burnet and Thomas. This hypothesis was abandoned shortly afterwards because of the absence of strong experimental evidence supporting the conc
## Abstract Oncogenic transformation in human and experimental animals is not necessarily followed by the appearance of a tumor mass. The immune system of the host can recognize tumor antigens by the presentation of small antigenic peptides to the receptor of cytotoxic Tβlymphocytes (CTLs) and reje