𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cancer gene therapy — new approaches to tumour cell killing


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
51 KB
Volume
2
Category
Article
ISSN
1099-498X

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✦ Synopsis


The aim of Dr Vile's laboratory at Mayo is the development of targeted and ef®cient vectors for the delivery of cytotoxic and immunostimulatory genes for the gene therapy of cancer.

JGM: Could you explain the herpes virus DISC vector approach?


📜 SIMILAR VOLUMES


New approaches to cancer therapies
✍ Fåhraeus, Robin; Fischer, Peter; Krausz, Eberhard; Lane, David P. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 222 KB 👁 2 views

Inactivation of the tumour suppressors p53 and p16 INK4a or activating mutations in the ras oncogene are the most common genetic alterations found in human cancers. In this review, novel approaches designed to evaluate the effect of targeting intracellular molecules are described and it is shown how