## Abstract Tumor suppressor genes are often silenced in human cancer; this can occur by transcriptional repression by deacetylation in the promoter regions, mediated by histone deacetylase (HDAC). HDAC inhibitors can block cancer cell growth by restoring expression of tumor suppressor genes. In th
β¦ LIBER β¦
Cancer biology: mechanism of antitumour action of vorinostat (suberoylanilide hydroxamic acid), a novel histone deacetylase inhibitor
β Scribed by Richon, V M
- Book ID
- 109999001
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 149 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0007-0920
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