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Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2

✍ Scribed by Agrawal, Babita; Krantz, Mark J.; Reddish, Mark A.; Longenecker, B. Michael

Book ID
109926828
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
942 KB
Volume
4
Category
Article
ISSN
1078-8956

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## Abstract Our aim was to examine the involvement of G~1~ cell‐cycle regulators in cell growth dysregulation induced by HTLV‐I. Compared to uninfected cells, higher expression levels of cyclin D1 and D2 mRNA were detected in HTLV‐I–infected T‐cell lines, which were at least in part mediated by the