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Can we prevent inhibitors in mild and moderate factor VIII-deficient patients?

โœ Scribed by L. M. ALEDORT


Book ID
109151417
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
74 KB
Volume
4
Category
Article
ISSN
1538-7933

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Amino acid substitutions in conserved do
โœ Carol Diamond; Scott Kogan; Barbara Levinson; Jane Gitschier ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 863 KB

Mutations leading to hemophilia A by substitution of amino acids in coagulation factor VIII may provide important clues to the structure and function of this large and enigmatic protein. To efficiently find missense mutations, hemophiliacs with mild and moderately severe forms of the disease were su