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Can tumor necrosis factor receptor II gene 676T>G polymorphism predict the response grading to anti-TNFα therapy in rheumatoid arthritis?

✍ Scribed by Alessia Ongaro; Monica De Mattei; Agnese Pellati; Angelo Caruso; Stefano Ferretti; Federica Francesca Masieri; Maria Fotinidi; Ilaria Farina; Francesco Trotta; Melissa Padovan

Book ID: 106007533
Publisher: Springer
Year: 2008
Tongue: English
Weight: 369 KB
Volume: 28
Category: Article
ISSN: 0172-8172
DOI: 10.1007/s00296-008-0552-5

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## Objective Several rheumatoid arthritis (RA) susceptibility variants map close to genes involved in the tumor necrosis factor (TNF) signaling pathway, prompting the investigation of RA susceptibility variants in studies of predictors of response to TNF blockade. Based on a previously reported ass