Can soman cause delayed neuropathy?
β Scribed by JOHNSON, M
- Book ID
- 123200890
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 133 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0272-0590
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π SIMILAR VOLUMES
The organophosphorus nerve agents soman and tabun were tested in the hen at doses 120-150 times higher than their acute LD50, as it was assumed that these doses would produce delayed neuropathy. The animals were protected against the acute lethal effect of these agents by pretreatment with atropine,
## Abstract Organophosphorus compounds are inhibitors of serine hydrolases. Some of these compounds produce, in addition to their high acute toxicity, a more persistent effect: organophosphateβinduced delayed neuropathy (OPIDN). The putative molecular entity whose inhibition is thought to be respon